Primary hypogonadism happens when something is wrong with your testicles that doesn’t allow them to make normal levels of testosterone.

Another name for primary hypogonadism is hypergonadotropic hypogonadism. In this type, your pituitary gland produces more luteinizing hormone (LH) and follicle-stimulating hormone (FSH) (known as gonadotropins) in response to low testosterone levels. The high levels of these hormones would normally tell your testicles to produce more testosterone and sperm. However, if you have damaged (most commonly related to prior chemotherapy) or missing testicles, they can’t respond to the increased levels of gonadotropins. As a result, your testicles make too little or no testosterone and sperm.

Sometimes in primary hypogonadism testosterone levels are within the normal range and gonadotropins are high. Your specialist will help you understand if you need treatment, even with normal testosterone levels.

Causes of Low Testosterone:

• Aging: Testosterone levels naturally decline with age, particularly after 30. 
• Medical Conditions: Conditions affecting the testicles (like testicular damage), pituitary gland, or hypothalamus can disrupt testosterone production. 
• Injuries or Infections: Trauma or infections can damage the testicles. 
• Certain Medications: Some medications can interfere with testosterone production. 
• Other factors: Obesity, diabetes, and metabolic syndrome can also be associated with low testosterone. 

Congenital conditions that affect your testicles and can lead to primary hypogonadism include:

• Absence of testicles at birth (anorchia).
• Undescended testicles (cryptorchidism).
• Leydig cell hypoplasia (underdevelopment of Leydig cells in your testicles).
• Klinefelter’s syndrome (a genetic condition in which males are born with an extra X chromosome: XXY instead of XY).
• Noonan syndrome (a rare genetic condition that can cause delayed puberty, undescended testicles or infertility).
• Myotonic dystrophy (part of a group of inherited disorders called muscular dystrophies).

Regular monitoring is essential to ensure the safety and effectiveness of TRT. This typically involves:

• Blood tests to check testosterone levels, liver function, and complete blood count.
• Prostate exams
• Cardiovascular monitoring
• Sleep assessment if sleep apnea is a concern

TRT can be a valuable treatment option for men with confirmed hypogonadism.

The first thing that we do to make sure that you get the right treatment is by getting certain tests done which would mostly include but not limit to CBC, Thyroid panel, Hormone Assay, Testosterone levels, androgen assay, sugar levels, HbA1c, urine analysis, DHEA levels, Cortisol levels, Liver function tests, Lipid profile, Vitamin B12 and D levels, serum electrolytes, iron panel. Based on this, we take further treatment for testosterone deficiency. Further testosterone replenishment planned as per infusions or oral therapies.

At HormoneHub, we utilize “the Elixir therapy” which is a holistic and multidimensional approach to balance the physiological hormones, overcome deficiencies, restore innate harmony, energize, rejuvenate and there by sustaining long term well-being. Our specialists in each segment inculcate the methodologies and techniques which one can practice lifetime and ensure the sustenance on own thereby.